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Human Health Campus
Human Health Campus
Human Health Campus

99mTc-MDP Uptake in Liver Metastases in a Patient with Gastric Carcinoma.

Teaching Case

Case presentation:

  • Male.
  • 67 y.o.
  • Complaint:abdominal pain for the past 4 months.
  • Initial treatment: as if viral gastroenteritis.
  • Evolution: persistent abdominal pain, mass sensation and gastrointestinal bleeding.
  • Blood tests: hemoglobin 7.7 g dl^(-1), whiste blood cell count 1600, neutrophil 310, platelets 55000.
  • Blood smear: immature granulocytes ando some nucleated red blood cells (suggestive of marrow infiltration by tumor).
  • Upper gastrointestinal endoscopy: 4cm corporo-antral gastric ulcer, Bormann III; gastric mucosa biopsy: intestinal-type adenocarcinoma, moderately well differentiated.
  • Abdominal ultrasound: Liver metastases, omental cake, retroperitoneal lymph node metastases.

Teaching points:

  • Regarding extraosseous Tc-99m MDP uptake:
  1. First rule out artifact: i. free pertechnetate uptake by stomach , thyroid and salivary glands. ii. radiopharmaceutical colloid formation uptake by liver, spleen and lungs. iii. Aluminium breakthrough. iv. Contamination. v. Gamma camera malfunction.

(More teaching points in the case).

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